Lecithin and Choline in Human Health and Disease (2024)

Article Navigation

Volume 52 Issue 10 October 1994
  • Next >

Journal Article

Get access

,

David J. Canty, M.S.

Department of Nutrition, Food, and Hotel Management at New York University, New York, NY

Search for other works by this author on:

Oxford Academic

Steven H. Zeisel, M.D., Ph D

University of North Carolina at Chapel Hill, Chapel Hill, NC

Search for other works by this author on:

Oxford Academic

Nutrition Reviews, Volume 52, Issue 10, October 1994, Pages 327–339, https://doi.org/10.1111/j.1753-4887.1994.tb01357.x

Published:

01 October 1994

Search

Close

Search

Advanced Search

Search Menu

Abstract

Choline is involved in methyl group metabolism and lipid transport and is a component of a number of important biological compounds including the membrane phospholipids lecithin, sphingomyelin, and plasmalogen; the neurotransmitter acetylcholine; and platelet activating factor. Although a required nutrient for several animal species, choline is not currently designated as essential for humans. However, recent clinical studies show it to be essential for normal liver function. Additionally, a large body of evidence from the fields of molecular and cell biology shows that certain phospholipids play a critical role in generating second messengers for cell membrane signal transduction. This process involves a cascade of reactions that translate an external cell stimulus such as a hormone or growth factor into a change in cell transport, metabolism, growth, function, or gene expression. Disruptions in phospholipid metabolism can interfere with this process and may underlie certain disease states such as cancer and Alzheimer's disease. These recent findings may be appropriate in the consideration of choline as an essential nutrient for humans.

This content is only available as a PDF.

© 1994 International Life Sciences Institute

Topic:

  • acetylcholine
  • platelet activating factor
  • alzheimer's disease
  • signal transduction
  • metabolism
  • gene expression
  • cancer
  • hormones
  • cell membrane
  • choline
  • growth factor
  • tissue membrane
  • neurotransmitters
  • lecithin
  • phospholipids
  • plasmalogens
  • second messenger systems
  • sphingomyelins
  • liver function
  • nutrients
  • essential nutrients
  • cellular biology
  • lipid transport

You do not currently have access to this article.

Download all slides

Sign in

Get help with access

Personal account

  • Sign in with email/username & password
  • Get email alerts
  • Save searches
  • Purchase content
  • Activate your purchase/trial code
  • Add your ORCID iD

Sign in Register

Institutional access

    Sign in through your institution

    Sign in through your institution

  1. Sign in with a library card
  2. Sign in with username/password
  3. Recommend to your librarian

Institutional account management

Sign in as administrator

Get help with access

Institutional access

Access to content on Oxford Academic is often provided through institutional subscriptions and purchases. If you are a member of an institution with an active account, you may be able to access content in one of the following ways:

IP based access

Typically, access is provided across an institutional network to a range of IP addresses. This authentication occurs automatically, and it is not possible to sign out of an IP authenticated account.

Sign in through your institution

Choose this option to get remote access when outside your institution. Shibboleth/Open Athens technology is used to provide single sign-on between your institution’s website and Oxford Academic.

  1. Click Sign in through your institution.
  2. Select your institution from the list provided, which will take you to your institution's website to sign in.
  3. When on the institution site, please use the credentials provided by your institution. Do not use an Oxford Academic personal account.
  4. Following successful sign in, you will be returned to Oxford Academic.

If your institution is not listed or you cannot sign in to your institution’s website, please contact your librarian or administrator.

Sign in with a library card

Enter your library card number to sign in. If you cannot sign in, please contact your librarian.

Society Members

Society member access to a journal is achieved in one of the following ways:

Sign in through society site

Many societies offer single sign-on between the society website and Oxford Academic. If you see ‘Sign in through society site’ in the sign in pane within a journal:

  1. Click Sign in through society site.
  2. When on the society site, please use the credentials provided by that society. Do not use an Oxford Academic personal account.
  3. Following successful sign in, you will be returned to Oxford Academic.

If you do not have a society account or have forgotten your username or password, please contact your society.

Sign in using a personal account

Some societies use Oxford Academic personal accounts to provide access to their members. See below.

Personal account

A personal account can be used to get email alerts, save searches, purchase content, and activate subscriptions.

Some societies use Oxford Academic personal accounts to provide access to their members.

Viewing your signed in accounts

Click the account icon in the top right to:

  • View your signed in personal account and access account management features.
  • View the institutional accounts that are providing access.

Signed in but can't access content

Oxford Academic is home to a wide variety of products. The institutional subscription may not cover the content that you are trying to access. If you believe you should have access to that content, please contact your librarian.

Institutional account management

For librarians and administrators, your personal account also provides access to institutional account management. Here you will find options to view and activate subscriptions, manage institutional settings and access options, access usage statistics, and more.

Purchase

Subscription prices and ordering for this journal

Purchasing options for books and journals across Oxford Academic

Short-term Access

To purchase short-term access, please sign in to your personal account above.

Don't already have a personal account? Register

Lecithin and Choline in Human Health and Disease - 24 Hours access

EUR €38.00

GBP £33.00

USD $41.00

Rental

Lecithin and Choline in Human Health and Disease (3)

This article is also available for rental through DeepDyve.

Advertisement

Citations

Views

130

Altmetric

More metrics information

Metrics

Total Views 130

16 Pageviews

114 PDF Downloads

Since 12/1/2016

Month: Total Views:
December 2016 2
February 2017 3
May 2017 1
June 2017 1
August 2017 3
September 2017 6
November 2017 2
December 2017 3
February 2018 3
March 2018 1
April 2018 2
May 2018 1
June 2018 2
October 2018 3
November 2018 1
March 2019 1
October 2019 1
November 2019 3
December 2019 2
April 2020 1
August 2020 1
December 2020 2
February 2021 1
April 2021 4
June 2021 2
August 2021 1
October 2021 1
November 2021 2
April 2022 1
May 2022 1
June 2022 2
July 2022 1
August 2022 1
September 2022 1
November 2022 3
December 2022 4
February 2023 5
March 2023 3
April 2023 3
May 2023 5
June 2023 2
July 2023 1
October 2023 6
December 2023 4
January 2024 6
March 2024 2
April 2024 3
May 2024 5
June 2024 3
July 2024 5
August 2024 1
September 2024 3
October 2024 3

Citations

Powered by Dimensions

Altmetrics

×

Email alerts

Article activity alert

Advance article alerts

New issue alert

Receive exclusive offers and updates from Oxford Academic

Citing articles via

Google Scholar

  • Latest

  • Most Read

  • Most Cited

The Effects of Subsidies for Healthy Foods on Food Purchasing Behaviors, Consumption Patterns, and Obesity/Overweight: A Systematic Review
The Effect of Algae Supplementation on Anthropometric Indices in Adults: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials
Vitamin D as a Modifiable Risk Factor for Juvenile Idiopathic Arthritis: A Systematic Review and Meta-analysis of Observational Studies Comparing Baseline Vitamin D in Children with JIA to Individuals Without
Micronutrients, Vitamin D, and Inflammatory Biomarkers in COVID-19: A Systematic Review and Meta-analysis of Causal Inference Studies
Mediterranean Diet and Risk of Hip Fracture: A Systematic Review and Dose-Response Meta-Analysis

More from Oxford Academic

Allied Health Professions

Dietetics and Nutrition

Medicine and Health

Books

Journals

Advertisement

Lecithin and Choline in Human Health and Disease (2024)

References

Top Articles
Latest Posts
Recommended Articles
Article information

Author: Dong Thiel

Last Updated:

Views: 6088

Rating: 4.9 / 5 (79 voted)

Reviews: 86% of readers found this page helpful

Author information

Name: Dong Thiel

Birthday: 2001-07-14

Address: 2865 Kasha Unions, West Corrinne, AK 05708-1071

Phone: +3512198379449

Job: Design Planner

Hobby: Graffiti, Foreign language learning, Gambling, Metalworking, Rowing, Sculling, Sewing

Introduction: My name is Dong Thiel, I am a brainy, happy, tasty, lively, splendid, talented, cooperative person who loves writing and wants to share my knowledge and understanding with you.